Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-11-17
1989-02-21
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142352, 544121, 544225, 544363, 544374, 544379, 544383, 546156, A61K 31505, C07D40110
Patent
active
048065390
ABSTRACT:
An antibacterial 1-cyclopropyl-6-fluoro-1,4- dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid of the formula ##STR1## in which R represents branched or straight-chain propyl or butyl which is optionally substituted by hydroxy or methoxy, unsubstituted tert.-butyl, 2-methylthioethyl, trifluoromethylthiomethyl, 2-trifluoromethylthioethyl, cycloalkyl with 3 to 6 carbon atoms, cycloalkenyl having 5 to 6 carbon atoms optionally substituted by hydroxyl, 1,1-dioxidotetrahydrothiophen-3-yl, cyclopropylmethyl, 1-phenethyl, furylmethyl, allyl or propargyl optionally substituted by phenyl and their pharmaceutically usable hydrates, acid addition salts, metal and guanidinium salts and prodrug forms.
REFERENCES:
patent: 4352803 (1982-10-01), Matsumoto et al.
patent: 4455310 (1984-06-01), Sakamoto et al.
patent: 4544658 (1985-10-01), Petersen et al.
patent: 4547503 (1985-10-01), Petersen et al.
patent: 4559342 (1985-12-01), Petersen et al.
patent: 4563459 (1986-01-01), Grohe et al.
patent: 4599334 (1986-07-01), Petersen et al.
patent: 4659603 (1987-04-01), Grohe et al.
Petersen et al., "Chemical Abstracts", vol. 101, 1984, col. 101:230575z.
Petersen et al., "Chemical Abstracts", vol. 102, 1985, col. 102:62271x.
Grohe et al., "Chemical Abstracts", vol. 101, 1984, col. 101:211165z.
Petersen et al., "Chemical Abstracts", vol. 102, 1985, col. 102:6525w.
Petersen et al., "Chemical Abstracts", vol. 102, 1985, col. 102:6526x.
Petersen et al., "Chemical Abstracts", vol. 104, 1986, col. 104:186447v.
Grohe et al., "Chemical Abstracts", vol. 104, 1986, col. 104:186448w.
Ito et al., "Chemical Abstracts", vol. 104, 1986, col. 104:186451s.
Hokr,, B02, 86-058972/09, J61010-574-A, Pharmaceuticals, p. 8, Week 8609.
Grohe Klaus
Metzger Karl G.
Petersen Uwe
Zeiler Hans-Joachim
Bayer Aktiengesellschaft
Hollrah Glennon H.
Turnipseed James H.
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