1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure

Details 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure

1982-12-30

1985-06-18

Waltz, Thomas A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

564104, C07C12914, A61K 31155

Patent

active

045241520

ABSTRACT:
1-Cyano-3-(fluoroalkyl)guanidines of the formula: ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 are the same or different members of the class of hydrogen, fluorine, lower alkyl or lower alkenyl provided that at least one member is fluorine or fluoro-substituted alkyl or alkenyl. These compounds are useful for their biological properties, e.g. in treating elevated blood pressure and Parkinson's disease.

REFERENCES:
patent: 2455894 (1948-12-01), Lecher et al.
patent: 2479498 (1949-08-01), Lecher et al.
patent: 2539558 (1951-01-01), Studeny et al.
patent: 2897162 (1959-07-01), Lowe et al.
patent: 3308022 (1967-03-01), Cummings et al.

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