Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-09-14
1988-12-27
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540355, 549549, 560150, 560159, 562564, A61K 31425, C07D20508, C07D41712, C07D30348
Patent
active
047941081
ABSTRACT:
A 2-azetidinone derivative having a group of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each represents a hydrogen atom, alkyl, aryl or arylalkyl which may have a substituent at the 1-position and an amino group, at the 3-position, which may be acylated or protected, its salt or ester, and methods of producing the same, (1) a method comprising subjecting a 2-azetidinone derivative having a group of the formula ##STR2## wherein the symbols are as defined above at the 1-position and an amino group at the 3-position, its salt or ester to an acylation or protective-group introduction reaction, and (2) a method comprising reacting a 2-azetidinone derivative having a hydroxy group at the 1-position and an amino group, at the 3-position, which may be acylated or protected, or its salt with a compound of the formula ##STR3## wherein W is a halogen atom; other symbols are as defined above, its salt or ester. The above objective compounds are utilizable as excellent antimicrobial agents or as valuable intermediates for the synthesis of the same.
REFERENCES:
patent: 4548747 (1985-10-01), Zahler
patent: 4548751 (1985-10-01), Kimball
Atherton, Chem. Abs. 101,6897y (1984).
Woulfe et al., Chem. Abs. 102, 6001x (1984).
Kishimoto Shoji
Ochiai Michihiko
Sendai Michiyuki
Berch Mark L.
Takeda Chemical Industries Ltd.
LandOfFree
1-carboxymethoxy acetidinones and their production does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1-carboxymethoxy acetidinones and their production, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-carboxymethoxy acetidinones and their production will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-868163