1-Carboxyalkyl derivatives of imidazoles

Details 1-Carboxyalkyl derivatives of imidazoles 1-Carboxyalkyl derivatives of imidazoles

1974-06-27

1976-04-20

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424273, C07D23360

Patent

active

039520056

ABSTRACT:
Imidazole derivatives substituted in the 1-position by a carboxyalkyl group or an ester of a such and the acid addition salts thereof, and where possible the alkali metal and alkaline earth metal salts thereof possess good antiphlogistic and analgesic activities. Such compounds are prepared, for example, by introducing the carboxyalkyl group or an ester of a such into the 1-position of a corresponding imidazole derivative unsubstituted in the 1-position. Alternatively such compounds are prepared by reacting an appropriate keto-oxime with an appropriate amino compound and an appropriate aldehyde or acetal and optionally reducing the imidazole derivative thus obtained.

REFERENCES:
patent: 3784691 (1974-01-01), Fitzi et al.
Lettau Zeit. Chem. 1970, Vol. 10, Heft. 9, pp. 338-339.
Lettau Zeit. Chem. 1970. Vol. 10, Heft. 11, pp. 431-432.
Lettau Zeit. Chem. 1970. Vol. 10, Heft. 12, p. 462.
Lettau Zeit. Chem. 1971, Vol. 11, Heft. 1, pp. 10-11.
Birkofer et al. Chem. Abst. 1961, Vol. 55, columns 5484-5485.
Bogatkov et al. Chem. Abst. 1972, Vol. 76, No. 59525x.
Ellis et al. J. Pharm. Pharmacol. 1964, Vol. 16, pp. 400-407.
Sunjic et al. I Chem. Abst. 1969, Vol. 71, No. 90645.
Sunjic et al. II Chem. Abst. 1971, Vol. 74, No. 22763f.
Toth et al. Chem. Abst. 1968, Vol. 69, No. 96719q.
Easson et al. J. Chem. Soc. (London) 1932, pp. 1806-1812.

Affiliated with

Also associated with

Rating

1-Carboxyalkyl derivatives of imidazoles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-Carboxyalkyl derivatives of imidazoles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-Carboxyalkyl derivatives of imidazoles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1587591