1-Carbamoyl-5-fluorouracil derivatives

Details 1-Carbamoyl-5-fluorouracil derivatives 1-Carbamoyl-5-fluorouracil derivatives

1976-09-24

1977-06-28

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424251, C07D23910

Patent

active

040325245

ABSTRACT:
1-Carbamoyl-5-fluorouracil derivatives represented by the formula ##STR1## wherein R.sub.1 represents methyl, ethyl, phenyl or cyclohexyl and R.sub.2 represents hydrogen or is the same as R.sub.1 are effective anti-metabolites useful in treating lymphatic leukemia L1210, sarcoma 180A and Ehrlich ascites carcinoma in mice.

REFERENCES:
ozaki, et al.; "Chemical Abstracts", vol. 82, 1975, col. 171016g.
Ozaki, et al.; "Chemical Abstracts", vol. 82, 1975, col. 140297v.
"Doklady Akademii Nauk SSSR", vol. 176 (2), 1967, pp. 332-335.

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