1-Carba(dethia)cephalosporin antibiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540205, 540222, C07D47104, A61K 31435

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active

051790882

ABSTRACT:
1-Carba(1-dethia)cephem antibacterial agents possessing a 3-(substituted or unsubstituted)thiazolo group are provided. Further provided is a method for treating bacterial infections in man and other animals and a pharmaceutical formulation utilziing said 1-carba(1-dethia)cephems.

REFERENCES:
patent: 5077287 (1991-12-01), Temansky
R. A. Firestone et al., J. of Medicinal Chemistry, 1977, vol. 20, No. 4, pp. 551-556.
Guthikonda et al., J. Am. Chem. Soc., 96, No. 24, pp. 7584-7585 (1974).
J. F. Peyronel et al., "Recent Advances in the Chemistry of .beta.-Lactam Antibiotics", Royal Society of Chemistry, London, 1985, Publ. No. 52, p. 336.

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