1-carba-2-penem-3-carboxylic acid

Details 1-carba-2-penem-3-carboxylic acid 1-carba-2-penem-3-carboxylic acid

1987-07-31

1988-10-04

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540350, C07D48704, A61K 3140

Patent

active

047756691

ABSTRACT:
Disclosed are 1-carba-2-penem-3-carboxylic acids of the following structure: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are, inter alia, independently selected from the group consisting of hydrogen, alkyl, aryl, and aralkyl. Such compounds as well as their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmacetical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 4260627 (1981-04-01), Christensen et al.
patent: 4543257 (1985-09-01), Cama et al.

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