Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1980-01-04
1985-09-24
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
2602452T, 260239A, C07D48704, A61K 3140
Patent
active
045432570
ABSTRACT:
Disclosed are 1-carba-2-penem-3-carboxylic acids of the following structure: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are, inter alia, independently selected from the group consisting of hydrogen, alkyl, aryl, and aralkyl. Such compounds as well as their pharmaceutically acceptable salt, ester and amide derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such compounds, pharmaceutical compositions comprising such compounds and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.
REFERENCES:
patent: 4196211 (1980-04-01), Christensen et al.
patent: 4203902 (1980-05-01), Shih
patent: 4260627 (1981-04-01), Christensen et al.
patent: 4262009 (1981-04-01), Christensen et al.
patent: 4267188 (1981-05-01), Cama et al.
Cama Lovji D.
Christensen Burton G.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Rizzo Nicholas S.
Speer Raymond M.
Szura Daniel T.
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