1-Benzyl-2-aminomethyl imidazole derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D23364

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active

045323313

ABSTRACT:
Potent DBH inhibitors having the formula: ##STR1## wherein R is --CO.sub.2 H or --CH.sub.2 NHR.sup.1 can be used to inhibit DBH activity in mammals.

REFERENCES:
patent: 3915980 (1975-10-01), Gebert et al.
Gerbert et al., Chemical Abstracts, vol. 72, No. 39275e.
Iversen et al., Acta Chem. Scand. 21:279-285 (1967).
Fuller et al., Adv. Enzyme Regulation 15:267-281 (1976).
Runti et al., Il. Farmaco Ed. Sc. 36:260-268 (1980).
Goldstein, Pharmacol. Rev. 18:77-82 (1966).

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