[1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents

Details [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents

1980-03-24

1981-05-19

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548359, A61K 31415, C07D49504, C07D48700

Patent

active

042685168

ABSTRACT:
1,2,3,4-Tetrahydrobenzothiopyrano[4,3-c]pyrazol-3-ones and 2,3-dihydro[1]benzothiopyrano[4,3-c]pyrazol-3-ones, of respective structure I and II, ##STR1## wherein n is an integer of value from 0 to 2;

REFERENCES:
patent: 3235564 (1966-02-01), Wagner
patent: 3816438 (1974-06-01), Houlihan
patent: 3932434 (1976-01-01), Paget
McCarty, Arthritis and Allied Conditions, pp. 375-390, Lea & Febiger, Philadelphia, 1979.
Pagani et al, Chem. Abst. 1971, vol. 75, No. 48829c.
Scrowston et al, J. Chem. Soc. 1976, Perkin Trans., pp. 749-754.
Huskisson et al, Lancet 1976, vol. 1, pp. 393-395.
Runge et al, Arth. and Rheum. 1977, vol. 20, pp. 1445-1448.
Schneller in "Advances in Heterocyclic Chemistry", vol. 18, Karitzky & Boulton, Eds., Academic Press, New York, 1975, pp. 88-94.

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