1-(Benzothien-2'-yl)-3-morpholino propanones and therapeutic com

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544146, C07D41306

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active

041698924

ABSTRACT:
Compounds having the formula ##STR1## wherein R.sub.1 and R.sub.2 are alkyls or alkenyls having one to 4 atoms or ##STR2## is pyrrolidino, piperidino, perhydroazepino or morpholino, and RX is a salt-forming moiety. The compounds are prepared by reacting 2-acetyl benzothiophene with ##STR3## The compounds possess a blood plaque aggregation inhibiting property and also possess spasmolytic, analgesic, anti-inflammatory and coronary, cerebral and peripheral vasodilatatory properties.

REFERENCES:
patent: 3417087 (1968-12-01), Campaigne et al.
patent: 3903092 (1975-09-01), Chapman et al.
Campaigne et al "Chem. Abstracts", vol. 62, (1965) p. 6829f.
Robba et al. "Chem. Abstracts", vol. 85, No. 192,540a (1976).

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