1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropion

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

5142332, 514253, 514278, 514305, 544 586, 544127, 544362, 546 16, 546137, A61K 31435, A61K 3154, A61K 31535, C07D45300

Patent

active

048430749

ABSTRACT:
Novel 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts and their use as antimuscarinic agents having antisecretory activity selective for the gastrointestinal tract are disclosed. The compounds have the formula: ##STR1## wherein: X=H, halogen, lower alkyl, lower alkoxy, hydroxy, and

REFERENCES:
patent: 4644003 (1987-02-01), Rzeszotarski et al.

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