1-aza-dibenzoazulenes as inhibitors of tumour necrosis...

Details 1-aza-dibenzoazulenes as inhibitors of tumour necrosis... 1-aza-dibenzoazulenes as inhibitors of tumour necrosis...

2007-12-25

2007-12-25

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

C514S410000, C514S431000, C514S450000, C548S406000, C548S421000, C549S004000, C549S012000, C549S214000, C549S354000

Reexamination Certificate

active

10515679

ABSTRACT:
The present invention relates to 1-aza-dibenzoazulene derivatives, to their pharmacologically acceptable salts and solvates, to processes and intermediates for the preparation thereof as well as to their antiinflammatory effects, especially to the inhibition of tumour necrosis factor-α (TNF-α) production and the inhibition of interleukin-1 (IL-1) production as well as to their analgetic action.

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