Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-02-21
1991-08-06
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514316, 514326, 514422, 514345, 514424, 5142355, 514252, 540547, 540602, 544130, 544141, 544372, 544365, 546188, 546208, 546216, 546243, 548523, 548542, 548551, A61K 3155, C07D40112, C07D40312
Patent
active
050378228
ABSTRACT:
The invention relates to the products of formula ##STR1## in which R represents the radical ##STR2## in which R.sub.1 at any position on the benzene ring represents a linear, branched or cyclic alkyl, alkenyl or alkynyl containing up to 8 carbon atoms, or the radical ##STR3## in which R.sub.2 and R.sub.3, which may be identical or different, represent a hydrogen atom or a linear alkyl, alkenyl or alkynyl containing up to 8 carbon atoms or form, together with the nitrogen atom to which they are attached, a carbonaceous heterocyclic radical optionally containing another hetero form, or the radical OR', R' representing hydrogen, a linear, branched or cyclic alkyl radical containing up to 8 carbon atoms or an aryl radical containing up to 14 carbon atoms, or the radical SR.sub.4 or S(O)R.sub.5, R.sub.4 and R.sub.5 representing a linear, branched or cyclic alkyl, alkenyl or alkynyl containing up to 8 carbon atoms, or R represents naphthyl optionally substituted with a radical R'.sub.1, R'.sub.1 having one of the definitions stated above for R.sub.1, and n represents the number 1 or number 2, to a process for the preparation thereof, to their application as medicinal products and to compositions containing them.
REFERENCES:
patent: 3117975 (1964-01-01), Bortnick et al.
patent: 4829079 (1989-05-01), Toja et al.
Drugs of the Future, vol. 10, No. 12 (1985) pp. 972-974.
Noller "Chemistry of Organic Compounds" 2nd Ed. (1987) p. 282 (Saunders).
March "Advanced Organic Chemistry" 3rd Ed. (1985) pp. 793-794 (Wiley).
Barzaghi Fernando
Galliani Giulio
Toja Emilio
Bond Robert T.
Roussel-Uclaf
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