1-arylsulphonyl-2-piperidinone derivatives, process and intermed

Details 1-arylsulphonyl-2-piperidinone derivatives, process and intermed 1-arylsulphonyl-2-piperidinone derivatives, process and intermed

1990-02-21

1991-08-20

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514316, 514318, 514319, 514327, 514347, 540597, 546188, 546193, 546216, 546294, 546194, A61K 3155, A61K 31445, C07D21196, C07D40102

Patent

active

050414364

ABSTRACT:
The invention relates to the products of formula ##STR1## in which R represents the radical ##STR2## in which R.sub.1 at any position on the benzene ring represents linear, branched or cyclic alkyl, alkenyl or alkynyl containing up to 8 carbon atoms, or the radical ##STR3## in which R.sub.2 and R.sub.3, which may be identical or different, represents hydrogen or linear alkyl, alkenyl or alkynyl containing up to 8 carbon atoms or form, together with the nitrogen atom to which they are attached, a carbonaceous heterocyclic radical optionally containing another hetero atom, or the radical OR', R' representing hydrogen, a linear, branched or cyclic alkyl containing up to 8 carbon atoms or aryl containing up to 14 carbon atoms, or the radical SR.sub.4 or S(O)R.sub.5, R.sub.4 and R.sub.5 representing linear, branched or cyclic alkyl, alkenyl, or alkynyl containing up to 8 carbon atoms, or R represents naphthyl optionally substituted with the radical R'.sub.1, R'.sub.1 being as defined above for R.sub.1, to a process and intermediates for the preparation thereof, to their application as medicinal products and to compositions containing them.

REFERENCES:
patent: 4217130 (1980-08-01), Tsuruta et al.
patent: 4585769 (1986-04-01), Roger
patent: 4833156 (1989-05-01), Sakakibara et al.
Chem. Abstract, 110:75307d (1989), Sakakibara et al.

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