1-aryloxy-3-(substituted aminoalkylamino)-2-propanols, pharmaceu

Details 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols, pharmaceu 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols, pharmaceu

1986-10-14

1989-03-07

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

5142375, 5142385, 514255, 514330, 514331, 514423, 514428, 514522, 514586, 514595, 514609, 544159, 544160, 544163, 544165, 544167, 544168, 544390, 544399, 544400, 544401, 546226, 546230, 546231, 548538, 548567, 548569, 558412, 558415, 558417, 558419, 558422, 564 27, 564 47, 564104, A61K 3117, A61K 31275, C07C 1252, C07C12700

Patent

active

048107255

ABSTRACT:
1-Aryloxy-3-(substituted aminoalkylamino)-2-propanols and pharmaceutically acceptable salts thereof have .beta.-adrenergic blocking activity with some cardioselectivity and hence are useful as anti-hypertensive, antianginal, antiarrhythmic and cardioprotective agents and in the treatment of elevated intraocular pressure such as glaucoma.

REFERENCES:
patent: 4131685 (1978-12-01), Smith
Wolff, Burger's Medicinal Chemistry, 4th Ed., Part III, pp. 310 and 311.

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