1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant

Details 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant

1982-06-14

1991-01-29

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540593, C07D22316, A61K 3155

Patent

active

049886908

ABSTRACT:
The invention relates to 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines of the formula ##STR1## wherein Y is the same or different and is hydrogen and lower alkoxy; X is hydrogen, halogen, lower alkyl, lower alkoxy, CF.sub.3, NO.sub.2, CN and NH.sub.2 ; R is hydrogen, lower alkyl, cycloalkyllower alkyl, ##STR2## Ar lower alkyl of the formula -alkylene ##STR3## where Z is hydrogen, lower alkyl, lower alkoxy, halogen, CF.sub.3, NO.sub.2 and NH.sub.2 ; and an alkylene amine of the formula ##STR4## where R.sub.1 and R.sub.2 are the same of different and are hydrogen and lower alkyl, and the pharmaceutically acceptable acid addition salts thereof.

REFERENCES:
Rehman et al J. Chem. Soc. pp. 68-51 (1967).
Likforman et al, E. R. Acad. Sci. Paris vol. 268, pp. 2340-2341 (1969).

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