Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1982-06-14
1991-01-29
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540593, C07D22316, A61K 3155
Patent
active
049886908
ABSTRACT:
The invention relates to 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines of the formula ##STR1## wherein Y is the same or different and is hydrogen and lower alkoxy; X is hydrogen, halogen, lower alkyl, lower alkoxy, CF.sub.3, NO.sub.2, CN and NH.sub.2 ; R is hydrogen, lower alkyl, cycloalkyllower alkyl, ##STR2## Ar lower alkyl of the formula -alkylene ##STR3## where Z is hydrogen, lower alkyl, lower alkoxy, halogen, CF.sub.3, NO.sub.2 and NH.sub.2 ; and an alkylene amine of the formula ##STR4## where R.sub.1 and R.sub.2 are the same of different and are hydrogen and lower alkyl, and the pharmaceutically acceptable acid addition salts thereof.
REFERENCES:
Rehman et al J. Chem. Soc. pp. 68-51 (1967).
Likforman et al, E. R. Acad. Sci. Paris vol. 268, pp. 2340-2341 (1969).
Davis Larry
Effland Richard C.
Klein Joseph T.
Hoechst-Roussel Pharmaceuticals Inc.
Rosenstock Jerome
Springer David B.
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