1-aryl-dibenzothiophenes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514337, 514397, 514382, 514365, 5462811, 548454, 5483151, 5483114, 549 6, 549 46, 549 43, A61K 3138, A61K 31405, C07D40900, C07D40500, C07D23302

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active

060018674

ABSTRACT:
This invention provides compounds of Formula I having the structure ##STR1## wherein: B and D are each, independently, hydrogen, halogen, --CN, alkyl of 1-6 carbon atoms, aryl, aralkyl of 6-12 carbon atoms;

REFERENCES:
Reaven, G. M. et al., Amer. J. Med., 60, Jan. 1976, pp. 80-88.
Stout, R. W., Metabolism, 34:12 Suppl. Dec. 1, 1985, pp. 7-12.
Pyorala, K. et al., Diabetes/Metabolism Reviews, 3:2, 1987, pp. 463-524.
Jarrett, R.J., Diabetes/Metabolism Reviews, 5:7, 1989, pp. 547-558.
Harris, M. I. et al., Diabetes in America, 1985, Chapter 29, pp. 1-48.
DeFronzo, R. A., et al., Diabetes Care, 14:3, Mar. 1991, pp. 173-194.
Haring, H. U., Diabetologia, 34, 1991, pp. 848-861.
Goldstein, B. J., J. Cell. Biochem., 48, 1992, pp. 33-42.
Ahmad F. et al., Biochima et Biophysica Acta, 1248, 1995, pp. 57-69.
Goldstein, B. J., Receptor, 3, 1993, pp. 1-15.
McGuire, M. C. et al., Diabetes, 40, Jul. 1991, pp. 939-983.
Sredy, J. et al., Metabolism, 44:8, Aug. 1995, pp. 1074-1081.
Brown, E. V. et al., J. Med. Chem., 14:1, 1971, pp. 84-85.
Kimura, T. et al., Tetrahedron Letters, 36:7, 1995, pp. 1079-1080.
Schuster, I. I. et al., J. Org. Chem. 53, 1988, pp. 5819-5825.
Han, B. H. et al., Tetrahedron Letters, 31:8, 1990, pp. 1181-1182.
Mitsunobu, O., Synthesis, Jan. 1981, pp. 1-28.
Lefker, B. A. et al., Tetrahedron Letters, 35:29, 1994, pp. 5205-5208.
Phillion, D. P. et al., Tetrahedron Letters, 27:13, 1986, 1477-1480.
Zask, A. et al., J. Med. Chem., 33, 1990, pp. 1418-1423.
Perich, J. W., et al., Synthesis, Feb. 1988, pp. 142-144.
Lanzetta, P. A. et al., Analytical Biochemistry, 100, 1979, pp. 95-97.
Meyerovitch, J. et al., J. Clin. Invest., 87, Apr. 1991, pp. 1286-1294.
Goldstein, B. J. et al., Molec. and Cell. Biochem., 109, 1992, pp. 107-113.
Coleman, D. L. et al., Diabetologia, 14, 1978, pp. 141-148.
Chang, A. Y. et al., Diabetes, 32, Spet. 1983, pp. 830-837.
Meyerovitch, J. et al., J. Clin. Invest., 84, Sep. 1989, pp. 976-983.

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