Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2006-05-16
2006-05-16
Lambkin, Deborah C. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C514S471000, C514S238200, C564S182000, C549S468000, C544S169000
Reexamination Certificate
active
07045551
ABSTRACT:
The present invention provides novel aryl hydroxyethyl amides and related derivatives having the general Formula Iwherein R1, R2, R3, R4, R5, R6, R7and A are as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said aryl hydroxyethyl amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain and anxiety.
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He Huan
L'Heureux Alexandre
Sun Li-Qiang
Wu Yong-Jin
Algieri Aldo A.
Bristol--Myers Squibb Company
Lambkin Deborah C.
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