1-Aryl 2-aminomethyl cyclopropane carboxylates (Z) as drugs in t

Details 1-Aryl 2-aminomethyl cyclopropane carboxylates (Z) as drugs in t 1-Aryl 2-aminomethyl cyclopropane carboxylates (Z) as drugs in t

1982-06-22

1985-03-26

Helfin, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

560 37, 560 43, 560 22, 2605136, 548579, 544402, 544106, 549483, A61K 3134, A61K 31215, A61K 31395, C07C 9324

Patent

active

045073180

ABSTRACT:
The present invention concerns new derivatives of 1-aryl 2-aminomethyl cyclopropane carboxylates (Z), their preparation and their use as useful drugs for the treatment of various pains.
The new derivatives of the present invention have the general formula I ##STR1## in which: R represents a hydrogen or halogen atom, a C.sub.1 to C.sub.4 lower alkyl group, a C.sub.1 to C.sub.4 lower alkoxy group, or a nitro, amino, sulfamoyl or hydroxy group;

REFERENCES:
Mouzin et al., Synthesis, (1978), 304-305.
Casadio et al., Boll. Chim. Farm., (1978), vol. 117, 331-342.

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