1-aryl-1-hydroxy-1-substitute d-3-(4-substituted-1-piperazinyl)-

Details 1-aryl-1-hydroxy-1-substitute d-3-(4-substituted-1-piperazinyl)- 1-aryl-1-hydroxy-1-substitute d-3-(4-substituted-1-piperazinyl)-

1989-06-27

1991-03-19

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514252, 544 60, 544121, 544360, 544372, 544380, 544394, 544399, A61K 31495, C07D29504

Patent

active

050011600

ABSTRACT:
Compounds are disclosed having the formula: ##STR1## in which R.sub.1 is a C.sub.1 l to C.sub.12 alkyl, said alkyl being straight or branched chain, saturated or unsaturated, monosubstituted or unsubstituted, said substituents being selected from piperidine, pyrrolidine, morpholine, thiomorpholine or cycloalkyl of 3 to 7 carbons, a cycloalkyl of 3 to 9 carbons, a lower alkylcycloalkyl of 4 to 9 carbons, or a polycycloalkyl of 2 to 3 rings containing 7 to 12 carbons;

REFERENCES:
patent: 3073842 (1963-01-01), Schlesinger et al.
patent: 3125577 (1964-03-01), Biel
patent: 3157656 (1964-11-01), Krapcho
patent: 3395146 (1968-07-01), Satzinger
patent: 3873546 (1975-03-01), Becker et al.
patent: 4476129 (1984-10-01), Gootjes et al.
Amos E. Light et al., Chem. Abst., vol. 51, 11657d (1957).
Chemical Abstracts, Col., vol. 6, p. 9044s.
Chemical Abstracts, Col., vol. 6, p. 9517s.

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