1-aryl-1-(1H-azol-1-ylalkyl)-1,3-dihydroisobenzofurans, related

Details 1-aryl-1-(1H-azol-1-ylalkyl)-1,3-dihydroisobenzofurans, related 1-aryl-1-(1H-azol-1-ylalkyl)-1,3-dihydroisobenzofurans, related

1985-02-01

1988-04-12

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548262, 548336, 544132, 544139, 544 79, 544121, 544130, 544357, 544360, 544366, 544270, 546210, 546189, 514234, 514255, 514324, 514385, 514316, C07D40506, A61N 43653, A61N 4350

Patent

active

047375086

ABSTRACT:
Novel compounds including 1-aryl-1-(1H-imidazol-1-ylmethyl)-1,3-dihydroisobenzofurans such as 1-(4-chlorophenyl)-1-(1H-imidazol-1-ylmethyl)-1,3-dihydroisobenzofuran, and 1-aryl-1-(1H-1,2,4-trizazol-1-ylmethyl)-1,3-dihydroisobenzofurans are disclosed. The corresponding benzo[c]thiopenes, isochromans, and isothiochromans and antifungal pharmaceutical compositions containing same, and methods of using said pharmaceutical compositions to elicit an antifungal response in warm blooded animals having a susceptible antifungal infection are also disclosed.

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