Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-06-01
1989-05-30
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544370, A61K 31495, C07D40306
Patent
active
048351547
ABSTRACT:
Potent dopamine-.beta.-hydroxylase inhibitors having the Formula ##STR1## that are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.
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patent: 4532331 (1985-06-01), Frazee et al.
patent: 4603130 (1986-07-01), Iemura et al.
Finkelstein Joseph A.
Kruse Lawrence I.
Daus Donald G.
Lourie Alan D.
McCarthy Mary E.
Shen Cecilia
SmithKline Beckman Corporation
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