Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...


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514345, 514351, 514408, 514438, 514456, 514657, 546290, 546296, 546300, 548517, 548518, 548557, 548558, 548564, 548566, 548579, 549 74, 549358, 549362, 549429, 549491, 558411, 564316, 564323, 564336, 564344, 564366, A61K 31135




Compounds of the formula ##STR1## and pharmaceutically acceptable salt thereof, wherein R.sup.2 is selected from hydroxy and lower alkoxy, R.sup.5 is lower alkyl, and R.sup.11 and R.sup.12 are independently selected from hydrogen, halo, hydroxy, methoxy, and lower alkyl, are selective .alpha..sub.2 adrenergic receptor antagonists useful in the treatment of glaucoma.

patent: 3419560 (1968-12-01), Bernstein et al.


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