1-amino thiorcyl benzimidazoyl-2-one compounds

Details 1-amino thiorcyl benzimidazoyl-2-one compounds 1-amino thiorcyl benzimidazoyl-2-one compounds

1992-02-21

1994-12-06

Higel, Floyd D.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

530327, 530328, 530329, 530330, 530331, 530333, 546199, 5483051, 5483064, 5483061, C07K 708, C07K 706, C07K 510, C07K 508, C07K 506

Patent

active

053711858

ABSTRACT:
This invention relates to 1-amino thioacylbenzimidazoyl-2-one derivatives having the formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are defined herein. These compounds are useful as thioacylating reagents. This invention also relates to a process for producing cyclic and linear thiopeptides using the thioacylating reagents of this invention. This invention further relates to intermediate anilide compounds, which are produced by reacting an ortho phenylene diamine with an amino acid chain or peptide. This invention also relates to intermediate thioanilide compounds, which are produced by thionating the intermediate anilide compounds. This invention further relates to a process for producing the thioacylating reagents of this invention by cyclizing the intermediate thioanilide compounds.

REFERENCES:
patent: 2927116 (1960-03-01), Davoll et al.
patent: 4835166 (1989-05-01), Kitaura et al.
patent: 5138061 (1992-08-01), Belleau et al.

Affiliated with

Also associated with

Rating

1-amino thiorcyl benzimidazoyl-2-one compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-amino thiorcyl benzimidazoyl-2-one compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-amino thiorcyl benzimidazoyl-2-one compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-215388