1-(.alpha.-Phenyl-o-tolyl)imidazoles

Details 1-(.alpha.-Phenyl-o-tolyl)imidazoles 1-(.alpha.-Phenyl-o-tolyl)imidazoles

1975-11-03

1976-11-16

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D23356

Patent

active

039924009

ABSTRACT:
Compounds of the formulae IV and V: ##SPC1##
wherein R.sub.0 and R.sub.1 are hydrogen or alkyl of 1 to 3 carbon atoms, inclusive; wherein R.sub.2 is hydrogen, fluoro, chloro, or trifluoromethyl; wherein R.sub.3 is hydrogen or fluoro with the proviso that R.sub.3 cannot be fluoro, if R.sub.2 is chloro or trifluoromethyl; and wherein R.sub.4 is hydrogen, fluoro, chloro, bromo, trifluoromethyl, or nitro, are obtained by a multi-step reaction from the corresponding .alpha.-(phenyl)-o-toluidine of the formula I: ##SPC2##
wherein R.sub.2, R.sub.3, and R.sub.4 are defined as above, by treating I in sequence with an alkyl ester of orthoformic acid the resulting product with 2-alkyl-2-(aminoalkyl)-1,3-dioxolane or a 2-amino-alkanone dialkyl ketal and finally with titanium tetrachloride to obtain compound IV, and oxidizing compound IV to obtain the corresponding compound V.

REFERENCES:
patent: 3717658 (1973-02-01), Metlesics et al.
patent: 3852303 (1974-12-01), Houlihan

Affiliated with

Also associated with

Rating

1-(.alpha.-Phenyl-o-tolyl)imidazoles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-(.alpha.-Phenyl-o-tolyl)imidazoles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-(.alpha.-Phenyl-o-tolyl)imidazoles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-670407