1.alpha.-hydroxy-25-keto-27-nor-cholecalciferol and processes fo

Details 1.alpha.-hydroxy-25-keto-27-nor-cholecalciferol and processes fo 1.alpha.-hydroxy-25-keto-27-nor-cholecalciferol and processes fo

1979-05-21

1981-04-28

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26023955R, 26023955C, C07J 900

Patent

active

042645131

ABSTRACT:
The invention provides new vitamin D derivatives as well as new intermediate compounds derived during the processes for preparing such new derivatives. The new derivatives have been identified as 1.alpha.-hydroxy-25-keto-27-nor-vitamin D.sub.3 and its acylates.
1.alpha.-hydroxy-25-keto-27-nor-vitamin D.sub.3 expresses excellent vitamin D-like activity and would find ready application as a substitute for vitamin D compounds in the treatment of disease states evincing calcium-phosphorous imbalance.

REFERENCES:
patent: 3993675 (1976-12-01), Uskokovic et al.
patent: 4105660 (1978-08-01), Jones
patent: 4145346 (1979-03-01), Jones et al.

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