1.alpha.-Hydroxy-24-EPI-vitamin D.sub.4

Details 1.alpha.-Hydroxy-24-EPI-vitamin D.sub.4 1.alpha.-Hydroxy-24-EPI-vitamin D.sub.4

1995-09-07

1998-05-26

Prior, Kimberly J.

Organic compounds -- part of the class 532-570 series

Organic compounds

9,10-seco-cyclopentanohydrophenanthrene ring system or...

C07C40100

Patent

active

057567832

ABSTRACT:
1.alpha.-Hydroxy-24-epi-vitamin D.sub.4 and novel intermediates formed in a novel method of preparing this compound. The method includes campesterol as a starting material which is converted to 24-epi-vitamin D.sub.4 which is in turn hydroxylated to 1.alpha.-hydroxy-24-epi-vitamin D.sub.4 via tosylated and cyclic derivatives of 24-epi-vitamin D.sub.4. 1.alpha.-Hydroxy-24-epi-vitamin D.sub.4 has been found to be bioactive.

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