Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-05-17
1980-12-02
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2603972, A61K 5139, C07J 900
Patent
active
042371252
ABSTRACT:
Novel 1.alpha.-hydroxy-24-dehydrovitamin D.sub.3 and its hydroxyl-protected derivatives; novel 1.alpha.-hydroxy-24-dehydroprevitamin D.sub.3 and its hydroxyl-protected derivatives; and novel 1.alpha.,3.beta.-dihydroxycholesta-5,7,24-triene or its hydroxyl-protected derivatives which are key intermediates for preparing the aforesaid compounds. Novel processes for preparing these compounds are also provided. 1.alpha.-Hydroxy-24-dehydrovitamin D.sub.3 has a pharmacological action of controlling the calcium metabolism of warm-blooded animals, and is useful as a prophylactic or therapeutic pharmaceutical for vitamin D deficient disease and related diseases.
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patent: 3928397 (1975-12-01), Ikekawa et al.
patent: 4022891 (1977-05-01), Takeshita et al.
patent: 4069321 (1978-01-01), Jones et al.
Tetrahedron Letters, 13, pp. 1107-1108, (1977), Onisko et al.
Fed. of European Biochemical Society Letters, 76, pp. 177-181, (1977), Ikekawa et al.
Bannai Kiyoshi
Ishizuka Seiichi
Kubo Junji
Naruchi Tatuyuki
Ohnuma Norio
Robinson Douglas W.
Teijin Limited
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