Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1980-04-21
1981-03-03
Roberts, Elbert L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
26023955R, C07J 900
Patent
active
042540453
ABSTRACT:
The invention provides new derivatives of vitamin D.sub.3, specifically, 1.alpha.-hydroxy-2.beta.-fluorocholecalciferol.
The compound is characterized by vitamin D-like activity as measured by its ability to stimulate intestinal calcium transport, mobilize calcium from bone, increase serum inorganic phosphorous and in their antirachitic acitivity. The compound could, therefore, find ready application as a substitute for vitamin D in its various known applications and in the treatment of various metabolic bone diseases.
REFERENCES:
patent: 3741996 (1973-06-01), DeLuca et al.
patent: 4046760 (1977-09-01), Jones et al.
DeLuca Hector F.
Ikekawa Nobuo
Morisaki Masuo
Oshida Jun-ichi
Tanaka Yoko
Bremer Howard W.
Roberts Elbert L.
Wisconsin Alumni Research Foundation
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