1.alpha., 25-dihydroxy-2.beta.-fluorovitamin D.sub.3

Details 1.alpha., 25-dihydroxy-2.beta.-fluorovitamin D.sub.3 1.alpha., 25-dihydroxy-2.beta.-fluorovitamin D.sub.3

1981-02-17

1981-12-22

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 900

Patent

active

043070256

ABSTRACT:
The invention provides new derivatives of vitamin D.sub.3, specifically, 1.alpha.,25-dihydroxy-2.beta.-fluorocholecalciferol.
The compound is characterized by vitamin D-like activity as measured by its ability to stimulate intestinal calcium transport, mobilization of calcium from bone, increase serum inorganic phosphorous and in their antirachitic activity. The compound, could, therefore, find ready application as a substitute for vitamin D in its various known applications and in the treatment of various metabolic bone diseases.

REFERENCES:
patent: 4263214 (1981-04-01), DeLuca et al.

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