Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-04-07
1977-05-03
Rush, Raymond V.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
71 92, 424269, C07D48704
Patent
active
040214419
ABSTRACT:
Compounds of the formula II: ##STR1## wherein R is cyclopropyl, cyclopropylmethyl, or allyl; wherein R', R", and R.sub.1 are hydrogen or alkyl of 1 to 3 carbon atoms inclusive; and wherein R.sub.2, R.sub.3, and R.sub.4 are hydrogen, alkyl as defined above, fluoro, chloro, bromo, nitro, trifluoromethyl, or alkylthio in which alkyl is defined as above, are prepared by reacting a compound of the formula I. ##STR2## wherein R", R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are defined as above, and wherein X is chlorine or bromine, with an amine of the formula ##STR3## wherein R and R' are defined as above. The compounds of formula II and the pharmacologically acceptable acid salts thereof have tranquilizing, sedative, antianxiety, and anticonvulsant activity and can be used in animals and birds.
REFERENCES:
patent: 3842090 (1974-10-01), Gall et al.
patent: 3870706 (1975-03-01), Allgeier et al.
patent: 3892763 (1975-07-01), Hester
Berneis Hans L.
Rush Raymond V.
The Upjohn Company
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