1-alkyl-1-azoniabicyclo' 2.2.2 octane carbamate derivatives...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C546S137000

Reexamination Certificate

active

07452904

ABSTRACT:
Carbamate of general formula (I), wherein R1, R2, and R3 are H, OH, NO2, SH, CN, F, Cl, Br, I, COOH, CONH2, (C1-C4)-alkoxycarbonyl, (C1-C4)-alkylsulfanyl, (C1-C4)-alkylsulfinyl, (C1-C4)-alkylsulfonyl, (C1-C4)-alkoxyl optionally substituted with one or several F, and (C1-C4)-alkyl optionally substituted with one or several F or OH; R4 is cycloalkyl, phenyl, heteroaryl or a bicyclic ring system; R5 is cycloalkyl, (C5-C10)-alkyl, a substituted (C1-C10)-alkyl; and X−is a physiologically acceptable anion. Carbamate (I) is selective M3receptor antagonists versus M2receptor and may be used for the treatment of urinary incontinence (particularly, the one caused by overactive bladder), irritable bowel syndrome, and respiratory disorders (particularly, chronic obstructive pulmonary disease, chronic bronchitis, asthma, emphysema, and rhinitis), as well as in ophthalmic interventions.

REFERENCES:
patent: 6916828 (2005-07-01), Farrerons Gallemi et al.
patent: 7115629 (2006-10-01), Farrerons Gallemi et al.
patent: 7208501 (2007-04-01), Buil Albero et al.
patent: 0 747 355 (1996-12-01), None
patent: 0 801 067 (1997-10-01), None
patent: 01/04118 (2001-01-01), None
patent: WO 02/051841 (2001-12-01), None
patent: 02/051841 (2002-07-01), None

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

1-alkyl-1-azoniabicyclo' 2.2.2 octane carbamate derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-alkyl-1-azoniabicyclo' 2.2.2 octane carbamate derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-alkyl-1-azoniabicyclo' 2.2.2 octane carbamate derivatives... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4030576

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.