1-Acyloxyalkyl esters of cephalosporin

Details 1-Acyloxyalkyl esters of cephalosporin 1-Acyloxyalkyl esters of cephalosporin

1984-08-03

1988-02-16

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540227, A61K 31545, C07D50156

Patent

active

047255927

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sub.1 stands for n-propyl or isopropyl; and R.sub.2 stands for n-butyl, isobutyl, n-pentyl, n-hexyl or 2-ethylbutyl, or a pharmaceutically acceptable salt thereof, processes for preparing the same and a pharmaceutical composition thereof are provided. The compound can orally be applied as antibiotics having improved bioavailability.

REFERENCES:
patent: 4080498 (1978-03-01), Numata et al.
patent: 4189479 (1980-02-01), Kakeya et al.
patent: 4497809 (1985-02-01), Yoshimura et al.
Takahashi, et al., Chem. Abstracts, 78, (1973), Entry 111337v.
Takahashi, et al., Chem. Abstracts, 78, (1973), Entry 124613g.

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