Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-07-12
1989-11-14
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514287, 546 64, 546162, A61K 3147, C07D40112
Patent
active
048808180
ABSTRACT:
There are disclosed compounds of the formula ##STR1## where X,Y are each independently hydrogen, loweralkyl, loweralkoxy, hydroxy, halogen, trifluoromethyl or nitro; R.sub.1 is hydrogen or loweralkyl; R.sub.2 ' is hydrogen or loweralkyl and R.sub.4 is hydrogen, loweralkyl or aryl, which are useful as hypotensive agents and as intermediates.
REFERENCES:
patent: 3152133 (1964-10-01), Lowrie
patent: 3646019 (1972-02-01), Actor et al.
Mann et al., Chemical Abstracts, vol. 54, No. 7706d, f and g (1960).
Medicinal Chemistry, (2nd. ed.) Burger, editor, Interscience Publ., pp. 42-43 (1960.
Hu Ong Helen
Schonafinger Karl
Bernhardt E.
Hoechst-Roussel Pharmaceuticals Inc.
Ikeda Tatsuya
Shah Mukund J.
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