1-((A-substituted phenyl-.omega.-substituted piperazinyl)alkenyl

Details 1-((A-substituted phenyl-.omega.-substituted piperazinyl)alkenyl 1-((A-substituted phenyl-.omega.-substituted piperazinyl)alkenyl

1987-09-30

1988-05-17

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544357, 544397, C07D40304, C07D29508, A61K 31505, A61K 31495

Patent

active

047451912

ABSTRACT:
The compounds ##STR1## in which R.sup.1 is 3-hydroxy, 4-hydroxy, 3-methoxy, 4-methoxy or 3,4-methylenedioxy; n is 1 or 2; and R.sup.2 is ##STR2## where R.sup.3 is hydrogen, alkoxy of 1 to 6 carbon atoms, halo or trifluoromethyl; or a pharmaceutically acceptable salt thereof possess anxiolytic and antidepressant activity and are useful in treating psychiatric disorders involving anxiety and/or depression.

REFERENCES:
patent: 3192112 (1965-06-01), Biel
patent: 3435036 (1969-03-01), Regnier et al.
patent: 4675319 (1987-06-01), Nardi et al.

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