1,8-dihydroxy-9-anthrones for treating warts or psoriasis

Details 1,8-dihydroxy-9-anthrones for treating warts or psoriasis 1,8-dihydroxy-9-anthrones for treating warts or psoriasis

1984-11-07

1989-09-12

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 3119

Patent

active

048660957

ABSTRACT:
The invention concerns adducts of 1,8-dihydroxy-9-anthrone, of formula: ##STR1## in which: R.sub.1 and R.sub.2, taken together, form one of the following divalent residues: ##STR2## R.sub.3, R.sub.4, R'.sub.4, R.sub.5 and R'.sub.5 representing H, an alkyl group having 1-8 C with the exception of R.sub.5 =R'.sub.5 =CH.sub.3, a monohydroxyalkyl group with 2-8 C, possibly interrupted by one or more oxygens, a cycloalkyl group having 4-6 C, a phenyl group, or a benzyl group.
Utilization of the compounds (I) in human or veterinary medicine, in particular in the treatment of psoriasis and or warts, and in cosmetics.

REFERENCES:
patent: 4465688 (1984-08-01), Shroot et al.
patent: 4558069 (1985-10-01), Shroot et al.
patent: 4666941 (1987-05-01), Shroot et al.
patent: 4717720 (1988-01-01), Shroot et al.
Greene, Protective Groups in Organic Synthesis, John Wiley & Sons, Inc., (1981), pp. 169-171.

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