1-(7-Carboxy-2-octynyl)imidazole derivatives, pharmaceutical com

Details 1-(7-Carboxy-2-octynyl)imidazole derivatives, pharmaceutical com 1-(7-Carboxy-2-octynyl)imidazole derivatives, pharmaceutical com

1981-10-22

1983-02-22

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548341, A61K 31415, C07D23360

Patent

active

043748457

ABSTRACT:
The imidazole derivatives of the general formula: ##STR1## (wherein R.sup.1 represents a hydrogen atom or straight- or branched-chain alkyl group of 1 to 4 carbon atoms), or pharmaceutically acceptable non-toxic salts thereof, which have a specifically inhibitory effect on the biosynthesis of thromboxane A.sub.2 (abbreviated as TXA.sub.2 hereafter) and are, therefore, useful as treating agents for disease caused by TXA.sub.2 such as inflammation, cerebral apoplexy, miocardial infarction, acute cardiac death, cardiostenosis and thrombus etc.

REFERENCES:
patent: 4256757 (1981-03-01), Hayashi et al.

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