1,7-annelated indolecarboxylic acid esters and -amides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514214, 514217, 514220, 514304, 514305, 540468, 540472, 540479, 540558, 540586, 540544, 540546, A61K 3155, A61K 3144, C07D49100, C07D48712

Patent

active

049854208

ABSTRACT:
The invention relates to new 1,7-annelated esters and amides of indolecarboxylic acids having general formula 2, ##STR1## wherein the symbols have the meanings given in the specification. The compounds and their salts are very strong and selective antagonists of "neuronal" 5-hydroxytryptamine (5-HT) receptors, and can be used for the treatment of symptoms which are caused by over-stimulation of these receptors.

REFERENCES:
patent: 4594190 (1986-06-01), Giani et al.

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