1,6-Naphthyridine derivatives, and antidinic and cerebral circul

Details 1,6-Naphthyridine derivatives, and antidinic and cerebral circul 1,6-Naphthyridine derivatives, and antidinic and cerebral circul

1979-10-10

1981-12-29

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

542434, 542469, 546122, A61K 31435, C07D47104

Patent

active

043082734

ABSTRACT:
This invention relates to the novel 1,6-naphthyridine derivatives useful as antidinic and/or cerebral circulation improver, such novel derivatives being represented by the following general formula: ##STR1## (wherein R is a C.sub.2-10 alkyl which may have hydroxyl, lower alkylcarbonyl, lower alkyloxycarbonyl or phenoxy as a substituent; a C.sub.2-10 unsaturated aliphatic hydrocarbon group having unsaturated double bond(s); a phenyl-lower alkyl which may have halogen, lower alkyl, lower alkoxy or lower alkylthio as substituent(s) attached to the phenyl ring; a cinnamyl which may have halogen, nitro, lower alkyl or lower alkoxy as substituent(s) attached to the phenyl ring; propargyl; 1-naphthylmethyl; 2-thenyl; cyclohexenyl; a cycloalkyl-lower alkyl with a 3- to 6-membered ring; 1/2(C.sub.2-4 alkylene); 1/2(butenylene), or diphenylmethyl, and in case two alkoxyl groups are present attached to the phenyl ring, they may be bonded to form a ring) and salt thereof.

REFERENCES:
Chemical Abstracts vol. 67 (1967) Item 32611Z, abstracting Haglid "Ark. KEMI," vol. 26, No. 41, pp. 489-495 (1967).

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