Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-07-30
1985-10-22
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 93, 544 60, 544126, 544361, C07D22122
Patent
active
045489416
ABSTRACT:
There are disclosed novel substituted and bridged pyridines which are useful as calcium channel blockers.
REFERENCES:
patent: 4024265 (1977-05-01), Bastian
Schramm et al., "Novel Dihydropyridines with Positive Intropic Action Through Activation of Ca.sup.+2 Channels", Nature, 303, 535-537, (6/9/83).
Bossert et al., "4-Aryldihydropyridines, A New Class of Highly Active Calcium Antagonists", Angew. Chem. Int. Ed. English 20, 762-769 (1981).
Halczenko Wasyl
Hartman George D.
Bucci Patricia Ann
DiPrima Joseph F.
Jiles Henry R.
Merck & Co. , Inc.
Mitri Salvatore C.
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