1,5-diphenylpyrazoles II as HSP90 inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C548S247000, C546S275400, C544S371000, C544S238000, C514S406000, C514S252050, C514S254050, C514S326000, C514S341000

Reexamination Certificate

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07906657

ABSTRACT:
Novel 1,5-diphenylpyrazole derivatives of the formula (I) in which R1-R6have the meanings indicated in claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

REFERENCES:
patent: 2005/0222230 (2005-10-01), Drysdale et al.
patent: 2006/0148817 (2006-07-01), Beswick et al.
patent: 2007/0072855 (2007-03-01), Barrilalonso et al.
patent: 2007/0112192 (2007-05-01), Beswick et al.
patent: WO 03/055860 (2003-07-01), None
patent: WO 2004/050087 (2004-06-01), None
patent: WO 2004/056782 (2004-07-01), None
patent: WO 2004/096212 (2004-11-01), None
patent: WO 2006/018082 (2006-02-01), None
patent: WO 2006/039977 (2006-04-01), None
Vippagunta, et al Advanced Drug Delivery Reviews 48 (2001) 3-26.

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