1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols

Details 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols

1981-09-08

1983-04-19

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

A61K 31335

Patent

active

043806538

ABSTRACT:
The novel 1-(2,3-dihydro-1,4-benzodioxin-2S-yl)-5-(2,3-dihydro-1,4-benzodioxin-2R-yl )-3-azapentane-1R,5S-diol, and pharmaceutically acceptable acid addition salts thereof, are efficacious antihypertensive and bradycardic agents. Pharmaceutical compositions, methods of preparation and novel intermediates are described.

REFERENCES:
patent: 3312592 (1967-04-01), Chodnekar et al.
patent: 4187313 (1980-02-01), Gschwend et al.
patent: 4212808 (1980-07-01), Gschwend et al.
patent: 4261907 (1981-04-01), Gschwend et al.
patent: 4313955 (1982-02-01), Huebner et al.
Fine Chemical Patents Journ. of Britain, vol. 4, No. 37, (8-19-64), No. 966866.
Chem. Abstracts 79:126411j, (1973).
J. Med. Chem. 13, 169, (1970).

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