1,5-benzodiazepine compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540567, 544 60, 544111, 544359, 546199, 546148, 546271, 546167, 548523, 548336, 548159, 548217, 548218, 548305, 548465, 549 59, 549472, C07D24312, A61K 3155

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active

046475613

ABSTRACT:
Compounds of formula ##STR1## wherein R.sub.4 is aryl or heterocyclo are disclosed. These compounds are useful as cardiovascular agents and especially as anti-hypertensive agents.

REFERENCES:
Miyano et al., Synthesis of 3,3-Dimethyl-2,3,4,5,10,11-hexahydro-11-phenyl-1H-dibenzo[b,e][1,4]-diazep in-1-one, A New Tricyclic System, Chem. Pharm. Bull., 20(7) 1588-89 (1972).
Okamoto et al. "Chem Pharm Bull" (Japan) vol. 29, No. 4, (1981) pp. 1165-1169.

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