1,5-anhydrohexitol nucleoside analogues

Details 1,5-anhydrohexitol nucleoside analogues 1,5-anhydrohexitol nucleoside analogues

1993-12-17

1997-03-04

Kunz, Gary L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 282, 536 2714, A61K 3170, C07H 1906, C07H 1916

Patent

active

056079222

ABSTRACT:
1,5-Anhydrohexitol nucleoside analogues represented by the general formula I: ##STR1## wherein the hexitol has the D-configuration and the carbon atom on which the base moiety and the X substituent stand both have the (S)-configuration and further wherein:

REFERENCES:
L. Dee Nord et al., Synthesis, Structure, and Biological Activity of Certain 2-Deoxy-.beta.-D-ribo-hexopyranosyl Nucleosides and Nucleotides, Journal of Medicinal Chemistry, vol. 30, No. 6 (1987), pp. 1044-1054.
Poul Hansen et al., Synthesis of 3'-Azido-2',3'-dideoxy-.beta.-D-arabino-hexopyranosyl Nucleosides Liebigs Annalen der Chemie, vol. 1990, No. 11 (1990) pp. 1079-1082.
Verheggen et al. J. Med. Chem. 36:2033-2040, 1993.

Affiliated with

Also associated with

Rating

1,5-anhydrohexitol nucleoside analogues does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,5-anhydrohexitol nucleoside analogues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,5-anhydrohexitol nucleoside analogues will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2146041