1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives havin

Details 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives havin 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives havin

1976-06-18

1977-06-21

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

A61K 31415

Patent

active

040312348

ABSTRACT:
This application relates to 1,5(6)-disubstituted benzimidazole-2-carbamate derivatives represented by the following formula: ##STR1## where R is lower alkyl having 1 to 4 carbon atoms; R.sup.1 is --SOR.sup.2, --SR.sup.5, --OR.sup.5 or M'(CH.sub.2).sub.n MR.sup.7 ; R.sup.2 is lower alkyl having from 1 to 6 carbon atoms, cycloalkyl having 3 to 7 carbon atoms, lower alkenyl or lower alkynyl having 3 to 6 carbon atoms, or aralkyl or aryl; R.sup.5 is lower alkenyl, lower alkynyl or aralkyl; R.sup.7 is lower alkyl having 1 to 4 carbon atom, or aryl; M and M' are independently O, S, ##STR2## n is 1-4; and R.sup.8 is lower alkyl having 1 to 12 carbon atoms optionally substituted with a --COOR group where R is lower alkyl having 1 to 4 carbon atoms, aryl or aralkyl. The R.sup.1 substitution is at the 5(6)-position.
The compounds are useful as pesticides, particularly as anthelmintic and antifungal agents.

REFERENCES:
patent: 3641048 (1972-02-01), Dittmar
patent: 3657267 (1972-04-01), Van Gelder et al.

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