1,5,6,11-Tetrahydro[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridine

Details 1,5,6,11-Tetrahydro[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridine 1,5,6,11-Tetrahydro[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridine

1978-06-23

1979-12-18

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544361, C07D47104

Patent

active

041795644

ABSTRACT:
Various 1,5,6,11-tetrahydrobenzo[5,6]cyclohepta[1,2-b]pyrazolo[4,3-e]pyridine derivatives and their salts of the formulas ##STR1## wherein R.sub.1 is lower alkyl, phenyl, or phenyl-lower alkyl; R.sub.2 is hydrogen, lower alkyl or phenyl; R.sub.3 is hydrogen, halogen, or lower alkoxy; R.sub.4 is hydrogen, ##STR2## R.sub.5 is hydrogen or lower alkoxy; R.sub.6 is hydrogen, ##STR3## n is an integer from 2 to 6; R.sub.7 and R.sub.8 are the same or different and each is lower alkyl or R.sub.7 and R.sub.8 taken together with the N-atom form a heterocyclic ring of the formula ##STR4## wherein R.sub.9 is hydrogen or lower alkyl; R.sub.10 and R.sub.11 are the same or different and each is hydrogen or lower alkyl or R.sub.10 and R.sub.11 taken together with the N-atom form a heterocyclic ring of the formula ##STR5## wherein R.sub.9 is as defined above; are disclosed. These compounds possess useful anti-inflammatory activity as well as psychotropic activity.

REFERENCES:
patent: 4018779 (1977-04-01), Hoehn et al.
patent: 4033970 (1977-07-01), Hoehn et al.
patent: 4062858 (1977-12-01), Hoehn et al.
patent: 4087433 (1978-05-01), Hoehn et al.
patent: 4128717 (1978-12-01), Hoehn et al.
Chemical Abstracts, vol. 88, 768CS, col. 1.

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