1,5,10,11-Tetrahydrobenzo[4,5]-cyclohepta[1,2-b]pyrazolo[4,3-e]p

Details 1,5,10,11-Tetrahydrobenzo[4,5]-cyclohepta[1,2-b]pyrazolo[4,3-e]p 1,5,10,11-Tetrahydrobenzo[4,5]-cyclohepta[1,2-b]pyrazolo[4,3-e]p

1977-03-28

1978-05-02

Ford, John M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424256, 542404, C07D47104

Patent

active

040874338

ABSTRACT:
Compounds of the formulas ##STR1## wherein R.sub.1 is lower alkyl, phenyl, benzyl or phenethyl; R.sub.2 is hydrogen, lower alkyl or phenyl; R is ##STR2## N IS AN INTEGER FROM 3 TO 6; R.sub.3 and R.sub.4 are each lower alkyl or R.sub.3 and R.sub.4 taken together with the N-atom form a heterocyclic ring of the formula ##STR3## wherein R.sub.5 is hydrogen, lower alkyl, or lower alkoxy; and pharmaceutically acceptable acid addition salts thereof are disclosed. These compounds and their salts possess central nervous system activity and are useful as anti-anxiety agents.

REFERENCES:
patent: 4018779 (1977-04-01), Hoehn et al.
patent: 4033970 (1977-07-01), Hoehn et al.

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