1,4-Substituted-quinolin-2(1H)-ones as CNS agents

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424258, A61K 3147

Patent

active

040325288

ABSTRACT:
Disclosed are compounds which are 1-alkyl-4-alkoxyquinolin-2(1H)-ones, e.g., 1-methyl-4-butoxyquinolin-2(1H)-one, and which are useful as CNS depressant agents. The compounds may be prepared, for example, by reacting a 1-alkyl-4-hydroxyquinolin-2(1H)-one with an alkyl halide in presence of base.

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