1,4-Napthoquinone derivatives and use thereof

Details 1,4-Napthoquinone derivatives and use thereof 1,4-Napthoquinone derivatives and use thereof

1983-07-06

1985-07-23

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

260396R, 514548, 514569, A61K 3119, A61K 3112, C07C 5012

Patent

active

045308454

ABSTRACT:
1,4-naphthoquinone derivatives represented by the following general formula: ##STR1## (wherein R.sup.1 represents a hydrogen atom, a hydroxy group, a lower alkoxy group or an arylthio group, R.sup.2 represents a carboxy group, an esterified carboxy group or an amidated carboxy group or, when taken together, R.sup.1 and R.sup.2 form a group of ##STR2## R.sup.3 represents a hydrogen atom or a lower alkyl group, R.sup.4 represents a lower alkyl group, R.sup.5 represents a hydrogen atom or a halogen atom, and R.sup.6 represents a hydrogen atom, a lower alkyl group or a lower alkanoyl group), and the salts of the carboxy group thereof, which are novel compounds having an anticoccidium activity, and which can be obtained by synthesis or, partly, by cultivation of Streptomyces auranticolor.

REFERENCES:
patent: 2301382 (1942-11-01), Dickey et al.
patent: 2311032 (1943-02-01), Dickey et al.
patent: 3578686 (1971-05-01), Tullar et al.
patent: 3953874 (1976-04-01), Aviram et al.

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